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Video: A quick explainer on the promise—and risks—of TrueDepth in the iPhone XS

Ars - Tue, 2018-09-18 14:11

Valentina Palladino and iOS developer Nathan Gitter explain Apple's TrueDepth camera. Click here for transcript. (video link)

Apple's new iPhones launch this week, and unlike last year, every one of the new devices comes equipped with the TrueDepth sensor array originally found in the iPhone X. Most consumers who are interested in Apple's products know that piece of technology drives Face ID (an authentication method by which you log into your phone just by showing it your face) and Animojis, those 3D animated characters in Messages that follow your facial expressions.

But Apple and the developers who make apps for its platforms have more applications for the 3D sensing tech planned in the future, and consumers might not be aware of them. In this video, Ars Technica's Valentina Palladino and iOS app developer Nathan Gitter talk about how TrueDepth works, what exciting things it might be used for in the future, and what users have to look out for in terms of privacy and security concerns.

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The Amputee Who Showed Everyone

NY Times - Tue, 2018-09-18 14:06
Shaquem Griffin of the Seattle Seahawks lost his hand but not his dream.

Justice, Spy World Veterans Warn Of Consequences If Trump Releases Secret Docs

NPR All Things Considered - Tue, 2018-09-18 14:02

The president wants to release Russia investigation materials out of transparency, he says. But national security pros say he's imperiling sensitive information and hurting DOJ in the long run.

(Image credit: AP)

Parts of a ‘Virtual’ Border Wall, Built With the Tech Behind Driverless Cars

NY Times - Tue, 2018-09-18 14:01
In a rural Texas county, lidar sensor technology is being tested as a way to spot illegal intruders from Mexico. That use could divide workers in Silicon Valley.

A New Art Season, a New Test of Survival

NY Times - Tue, 2018-09-18 14:00
The art market is in crisis, and the art fairs are largely to blame.

Dealmaster: Take $40 off a 32GB Amazon Fire HD 10 tablet

Ars - Tue, 2018-09-18 13:58

Enlarge (credit: TechBargains)

Greetings, Arsians! Courtesy of our friends at TechBargains, we have a fresh batch of deals to share. Today's list is headlined by another round of discounts on Amazon devices, including a deal that brings the Fire HD 10 tablet down to $110. That's $40 off its usual going rate.

The big caveat here: the deals are only applicable to Amazon Prime subscribers. If you're already a member (or if you have a free trial), the Fire HD 10 is still one of the better big-screen slates on the cheap. Its 10.1-inch, 1920x1200 resolution display is a step above tablets in this range (albeit a few steps below an iPad), making it a solid choice for basic video viewing or comic book reading. It runs fine, and it gets a decent 8-10 hours of battery life on average. It recently gained the ability to work like an Echo Show, too. You'll have to do a little legwork to get the Google Play Store onto it if that's what you're after. But that's nothing a quick Google search can't fix.

Other ongoing deals include the 4K Fire TV for $40, the Kindle Paperwhite for $80, and the cheapo Fire 7 tablet for $35. If you don't have Prime, fear not, as the Dealmaster also has discounts on Xbox One controllers, Samsung SSDs and microSD cards, some good Bluetooth audio gear, and more. Have a look for yourself below.

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Sources: Kavanaugh hearing may not happen on Monday

CNN - Tue, 2018-09-18 13:48
Republican sources on Capitol Hill say it's uncertain if the Senate Judiciary Committee hearing scheduled for Monday to address the sexual assault accusation against Supreme Court nominee Brett Kavanaugh will actually occur.

Pictures leak of the “Google Home Hub,” Google’s version of a smart display

Ars - Tue, 2018-09-18 13:47


Google's big hardware event is coming October 9, and we're getting a clearer picture of what to expect from the show as the days go by. The event is promoted as the "Pixel 3 launch event," but the company's previous two hardware events featured five or more product announcements. Besides the Pixel 3, a Pixelbook 2 is a good option, and with the launch of Google's Smart Display software on third-party hardware earlier this year, it seems inevitable that we'll soon see a first-party Google Smart Display.

As luck would have it, today MySmartPrice has scored pictures of the "Google Home Hub," a product that is clearly Google's flagship hardware for its Smart Display software. The device has a 7-inch touchscreen and basically looks like a 16:9 tablet mounted to Google Home Max. Some of the pictures, which look like a leaked store listing, show a few more specs: 802.11ac Wi-Fi at 2.4 and 5GHz, Bluetooth, an "Ambient light and color sensor," a "full-range speaker for crystal clear sound," and "far-field voice recognition." The listing shows the display available in two colors ("chalk" and "charcoal"), with Google's traditional mute switch on the back and what looks to be a video chat camera on the front.

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Inter Milan vs. Tottenham

CNN - Tue, 2018-09-18 13:45

Eating junk food tied to higher risk of cancers

CNN - Tue, 2018-09-18 13:16
You probably already know that junk food, though delicious, is bad for you. It can have negative health effects such as increasing your risk of heart disease, metabolic disease and even cancer. Now, researchers have used a new nutritional labeling system to tie a diet low in nutritional quality with increased risks of a number of types of cancers.

Matter: Why Your DNA Is Still Uncharted Territory

NY Times - Tue, 2018-09-18 13:00
Scientists are focusing on a relatively small number of human genes and neglecting thousands of others. The reasons have more to do with professional survival than genetics.

11 male GOP senators ganging up on a woman accuser would be a disaster for a party already in deep trouble with female voters

CNN - Tue, 2018-09-18 12:56
Plans for a dramatic, clarifying hearing featuring Supreme Court pick Brett Kavanaugh and the woman who accused him of sexual assault have descended into chaos and partisan bitterness.

Software could lead to personalized leukemia treatments

Futurity.org - Tue, 2018-09-18 12:54

Early findings from a new study could help in the development of immune-based treatments personalized to people with acute myeloid leukemia who are undergoing stem cell transplantation, researchers report.

“If you could identify and activate the immune cells from the stem cell donor that only target leukemia cells, and not normal, healthy cells, that would be a big win,” says Ben Vincent, an assistant professor in the School of Medicine division of hematology/oncology at the University of North Carolina-Chapel Hill and co-senior author of the paper, which appears in Blood Advances.

The new approach relies on the fact that a patient’s cells can have unique genetic signatures that produce proteins distinct from any proteins found in the stem cell donor. The patient’s proteins can serve as markers for the cancer cells’ destruction by the donor’s natural defense system, which is activated in the process of stem cell transplantation.

The researchers report that they were able to validate their method of using genetic sequencing and computer software to predict which of those patient sequences resulted in unique surface markers, or minor histocompatibility antigens. They confirmed the approach in a group of patients with myeloid leukemia.

The researchers tested whether their software could predict antigenic targets in a group of 101 leukemia patients who had undergone stem cell transplant. Using the software, they correctly identified 16 of 18 minor histocompatibility antigens that are known to occur in AML. In addition, they predicted more than 100 new minor histocompatibility antigen targets that could be expressed on an individual’s AML cells.

The image shows how researchers predicted minor histocompatability antigens in leukemia patients. They looked for genetic differences, or SNPs, between donors and patients that were expressed only in leukemia. (Credit: UNC-Chapel Hill)

Because AML does not have one clear immune target, the validation of multiple potential targets is crucial. Based upon their computational predictions, the researchers confirmed a new minor histocompatibility antigen that is commonly presented on AML cells, and subsequently identified immune responses to this antigen in four of nine AML patients who had undergone stem cell transplant. Given these properties, the antigen could serve as a new target for immunotherapies across a wide range of AML patients.

Looking ahead, the researchers want to optimize their software to predict the most common AML-associated minor histocompatibility antigens present in the US population, and then confirm these predicted antigens as valid immunotherapy targets.

They could potentially use their predictions to engineer donor immune cells to specifically target the cancer cell antigens while preventing graft-versus-host disease, in which the donor’s immune cells attack healthy tissues.

“We’ve developed a software package that predicts leukemia-specific immune targets in any leukemia patient undergoing a stem cell transplant based on DNA and RNA sequencing and demonstrated that these data can lead to actual targets expressed on leukemia cells,” Vincent says.

“The next step of our work is to use that information for patient-specific therapies to try to improve cure rates without making graft-versus-host disease worse.”

The National Institutes of Health, the National Cancer Institute, an ASCO Young Investigator Award,  the University Cancer Research Fund, and the Scott Neil Schwirck Fellowship funded the work.

Source: UNC-Chapel Hill

The post Software could lead to personalized leukemia treatments appeared first on Futurity.

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